Combining Antibody-Directed Presentation of IL-15 and 4-1BBL in a Trifunctional Fusion Protein for Cancer Immunotherapy
نویسندگان
چکیده
منابع مشابه
Combining antibody-directed presentation of IL-15 and 4-1BBL in a trifunctional fusion protein for cancer immunotherapy.
Influencing the cytokine receptor network that modulates the immune response holds great potential for cancer immunotherapy. Although encouraging results have been obtained by focusing on individual members of the common γ-chain (γc) receptor family and TNF receptor superfamily so far, combination strategies might be required to further improve the effectiveness of the antitumor response. Here,...
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ژورنال
عنوان ژورنال: Molecular Cancer Therapeutics
سال: 2013
ISSN: 1535-7163,1538-8514
DOI: 10.1158/1535-7163.mct-13-0282